Use of Disulfide “Staples” To Stabilize β-Sheet Quaternary Structure
نویسندگان
چکیده
منابع مشابه
X-ray Crystallographic Structure of an Artificial β-Sheet Dimer
This paper describes the X-ray crystallographic structure of a designed cyclic beta-sheet peptide that forms a well-defined hydrogen-bonded dimer that mimics beta-sheet dimers formed by proteins. The 54-membered ring macrocyclic peptide (1a) contains molecular template and turn units that induce beta-sheet structure in a heptapeptide strand that forms the dimerization interface. The X-ray cryst...
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ژورنال
عنوان ژورنال: Organic Letters
سال: 2009
ISSN: 1523-7060,1523-7052
DOI: 10.1021/ol901015a